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CUSTOM PEPTIDE SYNTHESIS
Build the peptide.Plan what comes next.
From milligram discovery batches to clinical and commercial cGMP supply, JYMed provides integrated custom synthesis services for standard, long, cyclic, modified, and other complex peptides. Our peptide-focused teams combine sequence and route assessment, process development, purification, analytical development, scale-up, and regulatory-ready manufacturing to move your program forward efficiently with one experienced partner.
- 17+
- years in peptide R&D
- 130+
- scientists
- 65+
- CDMO programs
- 13
- cGMP API lines
SERVICES BUILT AROUND YOUR PEPTIDE
Start where you are.
Scale without starting over.
Every project begins with its intended use, sequence complexity, quality target and future scale. We configure the route and documentation around those requirements.
Custom peptide synthesis & lead support
Research-grade custom peptides for screening, structural modification, reference standards and early feasibility studies.
- Typical scale: 10 mg to 10 g
- Route and sequence assessment
- Purity and analytical package aligned to use
Complex peptides & modifications
Scientific and manufacturing support for challenging sequences, non-natural building blocks and conjugated peptide formats.
- Long, cyclic and multi-disulfide peptides
- Lipopeptides, glycopeptides and PNAs
- Labeling, PEGylation and conjugation
Process, analytical & CMC development
Integrated development to establish a robust, scalable peptide process and a defensible quality control strategy.
- Typical scale: 1 g to 5 kg
- Process development and pilot scale-up
- Method development, validation and CMC documentation
GMP manufacture & lifecycle supply
Clinical and commercial peptide production supported by validation, regulatory documentation and continuous improvement.
- Late clinical scale: 200 g to 100 kg
- Commercial supply: 1 kg to 10+ tons
- Validation, regulatory support and lifecycle management
Why Choose JYMed Peptide
Integrated Custom Synthesis + CDMO Model for Optimal Results
TECHNOLOGY TOOLBOX
More than one way to solve a difficult sequence.
JYMed selects and combines synthesis, purification, analytical and formulation technologies around yield, impurity risk, manufacturability, cost and future scale.
Four proprietary platforms connect every stage within one integrated peptide development pathway.
01 · SYNTHESIS
Route-flexible development combining six synthesis approaches within one scalable platform.
Capabilities: SPPS · LPPS · PA-LPPS · HPPS · MP-SPPS · CF-SPPS
02 · PURIFICATION & ISOLATION
JY FIS™
Advanced purification and isolation platform
Integrated purification and isolation strategies designed around target purity, impurity profile, recovery and manufacturing scale.
- Continuous chromatography
- DAC HPLC Φ150–1200 mm
- Spray drying: 1–15 L/h
- Lyophilization and recrystallization
03 · ANALYTICS
FUSION®
Intelligent analytical development platform
Design of Experiments (DoE), automated screening and statistical modeling accelerate method development while strengthening robustness, validation readiness and lifecycle performance.
04 · FORMULATION
JY-LYO
Specialized freeze-drying formulation platform
Integrated formulation and cycle development coordinates pre-freezing strategy, sublimation pressure and drying temperature to minimize degradation and protect peptide quality during scale-up.
Recommended peptide purity for your research
The appropriate purity level depends on the intended application, analytical sensitivity and acceptable impurity profile.
≥95%
Purity
Recommended for high-precision analytical applications
- NMR analysis
- Structural and crystallography studies
- Quantitative reference standards
- High-sensitivity enzyme–substrate assays
- Quantitative receptor–ligand studies
- Advanced blocking and competition assays
90 – <95%
Purity
Recommended for quantitative and functional research
- Antigen preparation for antibody programs
- Quantitative enzyme activity assays
- Receptor-binding studies
- Blocking and competition experiments
- Quantitative ELISA and RIA
- Selected in vitro and in vivo studies
> 80%
Purity
Recommended for exploratory and qualitative studies
- Non-quantitative Western blot analysis
- Preliminary screening
- Assay feasibility studies
- Early exploratory research
The JYMed advantage
Why peptide teams choose JYMed
Specialized science, connected development and commercial manufacturing capabilities help reduce handoffs as peptide programs advance.
Peptide-focused expertise
More than 17 years in peptide R&D and a team of 130+ scientists support standard, long, cyclic, modified and other complex sequences.
One connected CRDMO path
Custom synthesis, process development, analytics, cGMP API manufacturing and sterile drug product services remain connected as requirements evolve.
Proprietary technology toolbox
JY XPPS™, JY FIS™, FUSION® and JY-LYO connect synthesis, purification, analytical development and freeze-drying within one technology framework.
Quality and regulatory readiness
Thirteen cGMP API lines and experience with both US FDA and NMPA inspections support the quality expectations of clinical and commercial programs.
Commercial scale with greener execution
Multi-ton peptide capacity is supported by commercial TFA-free options, large-scale acetonitrile and DMF recovery, and an EcoVadis Bronze Medal.
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Ready to Transform Your Vision into Reality?
Partner with JYMed Peptide to leverage our comprehensive peptide solutions and global expertise. Let’s embark on a journey to accelerate your project from concept to market with precision and care.